COMPARATIVE TRANSCRIPTOMIC ANALYSIS PROVIDES INSIGHTS INTO THE REGULATION OF ROOT-SPECIFIC SAPONIN PRODUCTION IN PANAX JAPONICUS

Comparative transcriptomic analysis provides insights into the regulation of root-specific saponin production in Panax japonicus

Abstract Panax japonicus, a traditional medicinal plant from the Araliaceae family, produces bioactive triterpenes with health benefits.In Traditional Chinese Medicine, its roots have been used, but the chemical basis of its medicinal use is unclear, particularly regarding the metabolism and regulation of triterpene saponin biosynthesis.This study

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IL-21R-STAT3 signalling initiates a differentiation program in uterine tissue-resident NK cells to support pregnancy

Abstract Tissue-resident Natural Killer (trNK) cells are crucial components of local immunity that activate rapidly upon infection.However, under steady state conditions, their responses are read more tightly controlled to prevent unwanted tissue damage.The mechanisms governing their differentiation and activation are not fully understood.Here, we

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